Human IL4RA Protein; mFc Tag
Product Sizes
50 µg
£680.00
32-18254-50UG
100 µg
£815.00
32-18254-100UG
About this Product
- SKU:
- 32-18254
- Additional Names:
- CD124;IL-4RA;IL4RA
- Extra Details:
- Description :Recombinant Human IL4RA with C-terminal mouse Fc tag Background : This gene encodes the alpha chain of the interleukin-4 receptor; a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein; and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy; a condition that can manifest itself as allergic rhinitis; sinusitus; asthma; or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. Molecular Characterization: mass of 49.8 kDa after removal of the signal peptide.The apparent molecular mass of IL4RA-mFc is approximately 70-100 kDa due to glycosylation. Tag :C-Mouse Fc Tag
- Host:
- HEK293
- Purification:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
