Human PSMA Protein; hFc Tag
Product Sizes
50 µg
£680.00
32-18249-50UG
100 µg
£815.00
32-18249-100UG
About this Product
- SKU:
- 32-18249
- Additional Names:
- FGCP;FOLH;GCP2;GCPII;mGCP;NAALAD1;NAALAdase;PSM;PSMA
- Extra Details:
- Description :Recombinant human PSMA protein with N-terminal human Fc tag Background : This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates; including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate; central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates; resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms. Molecular Characterization: mass of 105.7 kDa after removal of the signal peptide.The apparent molecular mass of hFc-PSMA is approximately 130 kDa due to glycosylation. Tag :N-Human Fc Tag
- Host:
- HEK293
- Purification:
- The purity of the protein is greater than 90% as determined by SDS-PAGE and Coomassie blue staining.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
