Recombinant Human FGFR3 Protein; His Tag
Product Sizes
50 µg
£750.00
32-18224-50UG
100 µg
£911.00
32-18224-100UG
About this Product
- SKU:
- 32-18224
- Additional Names:
- ACH; CD333; CEK2; HSFGFR3EX; JTK4
- Extra Details:
- Molecular Characterization: FGFR3(Glu23-Gly375)6Ã-His tagMolecular weight: The protein has a predicted molecular mass of 39.0 kDa after removal of the signal peptide. The apparent molecular mass of FGFR3-His is approximately 55-70 kDa due to glycosylation.Description: Recombinant human FGFR3 protein with C-terminal6Ã-His tagThis gene encodes a member of the fibroblast growth factor receptor (FGFR) family; with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region; composed of three immunoglobulin-like domains; a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors; setting in motion a cascade of downstream signals; ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia.
- Host:
- HEK293
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
