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Recombinant Human GIPR Protein; hFc Tag

Product Sizes
50 µg
£656.00
32-18204-50UG
100 µg
£781.00
32-18204-100UG
About this Product
SKU:
32-18204
Additional Names:
PGQTL2
Extra Details:
Molecular Characterization: GIPR(Arg22-Gln138) hFc(Glu99-Ala330)Molecular weight: The protein has a predicted molecular mass of 39.6 kDa after removal of the signal peptide. The apparent molecular mass of GIPR-hFc is approximately 35-55 kDa due to glycosylation.Description: Recombinant Human GIPR Protein with C-terminal human Fc tagThis gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP); which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release; but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes.
Host:
HEK293
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules