Recombinant Human IL12A & IL12B Heterodimer Protein; hFc Tag & His Tag
Product Sizes
50 µg
£622.00
32-18203-50UG
100 µg
£732.00
32-18203-100UG
About this Product
- SKU:
- 32-18203
- Additional Names:
- CLMF; IL-12A; NFSK; NKSF1; P35 & CLMF; CLMF2; IL-12B; IMD28; IMD29; NKSF; NKSF2
- Extra Details:
- Molecular Characterization: IL12A(Arg23-Ser219) hFc(Glu99-Ala330)and IL12B(Ile23-Ser328)6Ã-His tagMolecular weight: The protein has a predicted molecular mass of 48.7 and 35.5 kDa after removal of the signal peptide.Description: Recombinant Human IL12A Protein with C-terminal human Fc tag and Human IL12B Protein with C-terminal6Ã-His tagInterleukin 12 (IL12) is also known as p70; and is an interleukin that is naturally produced by dendritic cells; macrophages and human B-lymphoblastoid cells (NC-37) in response to antigenic stimulation.IL12 is a heterodimeric cytokine; containing IL-12A (p35) and IL-12B (p40). IL-12 is involved in the differentiation of naive T cells into Th1 cells. It is known as a T cell-stimulating factor; which can stimulate the growth and function of T cells. It stimulates the production of IFN-ÃŽ³ and TNF-a from T cells and NK cells; and reduces IL-4 mediated suppression of IFN-ÃŽ³. IL-12 plays an important role in the activities of natural killer cells and T lymphocytes. IL-12 also has anti-angiogenic activity; which means it can block the formation of new blood vessels.
- Host:
- HEK293
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
