Recombinant Human TNFRSF1B Protein; His Tag
Product Sizes
50 µg
£635.00
32-18202-50UG
100 µg
£752.00
32-18202-100UG
About this Product
- SKU:
- 32-18202
- Additional Names:
- CD120b; p75; p75TNFR; TBPII; TNF-R-II; TNF-R75; TNFBR; TNFR1B; TNFR2; TNFR80
- Extra Details:
- Molecular Characterization: TNFRSF1B(Leu23-Asp257)6Ã-His tagMolecular weight: The protein has a predicted molecular mass of 26.0 kDa after removal of the signal peptide. The apparent molecular mass of TNFRSF1B-His is approximately 35-55 kDa due to glycosylation.Description: Recombinant Human TNFRSF1B Protein with C-terminal6Ã-His tagThe protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins; c-IAP1 and c-IAP2; which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown; however; c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2; which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
- Host:
- HEK293
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
