Recombinant Human MRGPRX2 Protein; hFc Tag
Product Sizes
50 µg
£622.00
32-18198-50UG
100 µg
£732.00
32-18198-100UG
About this Product
- SKU:
- 32-18198
- Additional Names:
- MGRG3; MRGX2
- Extra Details:
- Molecular Characterization: MRGPRX2(Met1-Pro33) hFc(Glu99-Ala330)Molecular weight: The protein has a predicted molecular mass of 29.6 kDa after removal of the signal peptide. The apparent molecular mass of MRGPRX2-hFc is approximately 35-55 kDa due to glycosylation.Description: Recombinant Human MRGPRX2 Protein with C-terminal human Fc tagMast cell-specific receptor for basic secretagogues; i.e. cationic amphiphilic drugs; as well as endo- or exogenous peptides; consisting of a basic head group and a hydrophobic core (PubMed: 25517090). Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ); such as non-steroidal neuromuscular blocking drugs (NMBDs); including tubocurarine and atracurium. In response to these compounds; mediates pseudo-allergic reactions characterized by histamine release; inflammation and airway contraction (By similarity). Acts as a receptor for a number of other ligands; including peptides and alkaloids; such as cortistatin-14; proadrenomedullin N-terminal peptides PAMP-12 and; at lower extent; PAMP-20; antibacterial protein LL-37; PMX-53 peptide; beta-defensins; and complanadine A.[UniProtKB/Swiss-Prot Function]
- Host:
- HEK293
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
