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Recombinant Human KREMEN2 Protein; His Tag

Product Sizes
50 µg
£656.00
32-18190-50UG
100 µg
£781.00
32-18190-100UG
About this Product
SKU:
32-18190
Additional Names:
KRM2
Extra Details:
Molecular Characterization: KREMEN2(Gly26-Ala364)6Ã-His tagMolecular weight: The protein has a predicted molecular mass of 36.8 kDa after removal of the signal peptide.Description: Recombinant Human KREMEN2 Protein with C-terminal6Ã-His tagThis gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor. A similar protein in mouse functions interacts with with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6); and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle; WSC; and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.
Host:
HEK293
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules