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TRAIL Recombinant Protein

Product Sizes
50 µg
£528.00
32-1819-50UG
About this Product
SKU:
32-1819
Additional Names:
Tumor necrosis factor ligand superfamily member 10||TNF-related apoptosis-inducing ligand||Protein TRAIL||Apo-2 ligand||Apo-2L||CD253 antigen||TL2||APO2L||TNFSF10.
Extra Details:
Source : Escherichia Coli. TRAIL/APO 2 Ligand Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 168 amino acids (Met+Arg115-Gly281) and having a molecular mass of ~21kDa. The sTRAIL is purified by proprietary chromatographic techniques. TNF-related apoptosis-inducing ligand (TRAIL) is a ligand molecule which induces apoptosis. It is a type II transmembrane protein with homology to other members of the tumor necrosis factor family.In humans; the gene that encodes for TRAIL is located at chromosome 3q26. TRAIL binds to the death receptors; DR4 and DR5. The process of apoptosis is caspase-8-dependent. This protein preferentially induces apoptosis in transformed and tumor cells; but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues.
Purification:
Greater than 95.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Lyophilized APO 2 Ligand although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution TRAIL should be stored at 4[o]C between 2-7 days and for future use below -18[o]C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg