Recombinant Human LAIR1 Protein; hFc Tag
Product Sizes
50 µg
£622.00
32-18189-50UG
100 µg
£732.00
32-18189-100UG
About this Product
- SKU:
- 32-18189
- Additional Names:
- CD305; LAIR-1
- Extra Details:
- Molecular Characterization: LAIR1(Gln22-His163) hFc(Glu99-Ala330)Molecular weight: The protein has a predicted molecular mass of 41.6 kDa after removal of the signal peptide. The apparent molecular mass of LAIR1-hFc is approximately 35-70 kDa due to glycosylation.Description: Recombinant Human LAIR1 Protein with C-terminal human Fc tagThe protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells; including natural killer cells; T cells; and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster; which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1; and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants.
- Host:
- HEK293
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
