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Recombinant Human ACVRL1 Protein; hFc Tag

Product Sizes
50 µg
£622.00
32-18175-50UG
100 µg
£732.00
32-18175-100UG
About this Product
SKU:
32-18175
Additional Names:
ACVRLK1; ALK-1; ALK1; HHT; HHT2; ORW2; SKR3; TSR-I
Extra Details:
Molecular Characterization: ACVRL1(Asp22-Gln118) hFc(Glu99-Ala330)Molecular weight: The protein has a predicted molecular mass of 36.8 kDa after removal of the signal peptide. The apparent molecular mass of ACVRL1-hFc is approximately 35-70 kDa due to glycosylation.Description: Recombinant Human ACVRL1 Protein with C-terminal human Fc tagThis gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains; a glycine- and serine-rich region (called the GS domain) preceding the kinase domain; and a short C-terminal tail. The encoded protein; sometimes termed ALK1; shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2; also known as Rendu-Osler-Weber syndrome 2.
Host:
HEK293
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules