Recombinant Human TIMP1 Protein; hFc Tag
Product Sizes
50 µg
£622.00
32-18133-50UG
100 µg
£732.00
32-18133-100UG
About this Product
- SKU:
- 32-18133
- Additional Names:
- CLGI; EPA; EPO; HCI; TIMP; TIMP-1
- Extra Details:
- Molecular Characterization: TIMP1(Cys24-Ala207) hFc(Glu99-Ala330)Molecular weight: The protein has a predicted molecular mass of 46.8 kDa after removal of the signal peptide. The apparent molecular mass of TIMP1-hFc is approximately 55-70 kDa due to glycosylation.Description: Recombinant Human TIMP1 Protein with C-terminal human Fc tagThis gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs); a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs; the encoded protein is able to promote cell proliferation in a wide range of cell types; and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition; the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.
- Host:
- HEK293
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
