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Recombinant Human VPS4 Protein; His Tag

Product Sizes
50 µg
£635.00
32-18111-50UG
100 µg
£752.00
32-18111-100UG
About this Product
SKU:
32-18111
Additional Names:
CIMDAG; SKD1; SKD1A; SKD2; VPS4A; VPS4-1
Extra Details:
Molecular Characterization: VPS4(Met1-Ser437)6Ã-His tagMolecular weight: The protein has a predicted molecular mass of 49.7 kDa after removal of the signal peptide. The apparent molecular mass of VPS4-His is approximately 55-70 kDa due to glycosylation.Description: Recombinant Human VPS4 Protein with C-terminal6Ã-His tagThe protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities); and is the homolog of the yeast Vps4 protein. In humans; two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other; and also with yeast Vps4 and mouse Skd1 proteins. The mouse Skd1 (suppressor of K transport defect 1) has been shown to be really an yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments; and are involved in intracellular protein trafficking; similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 16; the gene for the other resides on chromosome 18.
Host:
HEK293
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules