Recombinant Human PRTN3 Protein; His Tag

Product Sizes

50 µg

£823.00

32-18098-50UG

100 µg

£1019.00

32-18098-100UG

About this Product

SKU:: 32-18098
Additional Names:: ACPA; AGP7; C-ANCA; CANCA; MBN; MBT; NP-4; NP4; P29; PR-3; PR3
Extra Details:: Molecular Characterization: PRTN3(Ala26-Pro256)6Ã-His tagMolecular weight: The protein has a predicted molecular mass of 26.2 kDa after removal of the signal peptide. The apparent molecular mass of PRTN3-His is approximately 25-35 kDa due to glycosylation.Description: Recombinant Human PRTN3 Protein with C-terminal6Ã-His tagSerine protease that degrades elastin; fibronectin; laminin; vitronectin; and collagen types I; III; and IV (in vitro) (PubMed: 3198760; PubMed: 2033050; PubMed: 28240246). By cleaving and activating receptor F2RL1/PAR-2; enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration (PubMed: 23202369). May play a role in neutrophil transendothelial migration; probably when associated with CD177 (PubMed: 22266279).[UniProtKB/Swiss-Prot Function]
Host:: HEK293
Shipping Conditions:: Blue Ice
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: Abeomics
Type:: Proteins, Peptides, Small Molecules & Other Biomolecules

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