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Recombinant Human FGF-19 (N-6His) Protein

Product Sizes
50 µg
£726.00
32-18076-50UG
About this Product
SKU:
32-18076
Additional Names:
Fibroblast growth factor 19; FGF-19; FGF19
Extra Details:
Molecular weight: 23.5 KDaDescription: Recombinant Human Fibroblast Growth Factor 19 is produced by our E.coli expression system and the target gene encoding Phe27-Lys216 is expressed with a 6His tag at the N-terminus.Fibroblast growth factor 19 (FGF19) is a secreted protein which belongs to the FGFs family. FGF19 is expressed in fetal brain; cartilage; retina; and adult gall bladder. FGFs modulate cellular activity via at least 5 distinct subfamilies of high-affinity FGF receptors (FGFRs): FGFR-1; -2; -3; and -4; all with intrinsic tyrosine kinase activity. FGFRs can be important for regulation of glucose and lipid homeostasis. FGF19 has important roles as a hormone produced in the ileum in response to bile acid absorption. It has been shown to cause resistance to diet-induced obesity and insulin desensitization and to improve insulin; glucose; and lipid profiles in diabetic rodents. FGF19 can be considered as a regulator of energy expenditure.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules