Recombinant Human NLRP3 Protein; Flag Tag
Product Sizes
50 µg
£805.00
32-18010-50UG
100 µg
£994.00
32-18010-100UG
About this Product
- SKU:
- 32-18010
- Additional Names:
- AGTAVPRL; AII; AVP; C1orf7; CIAS1; CLR1.1; DFNA34; FCAS; FCAS1; FCU; KEFH; MWS; NALP3; PYPAF1
- Extra Details:
- Molecular Characterization: NLRP3?Lys2-Trp1036?+Flag Molecular Weight: The protein has a predicted molecular mass of 121.8 kDa after removal of the signal peptide. Description: Recombinant Human NLRP3 with C-terminal Flag tag This gene encodes a pyrin-like protein containing a pyrin domain; a nucleotide-binding site (NBS) domain; and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC; which contains a caspase recruitment domain; and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling; and it plays a role in the regulation of inflammation; the immune response; and apoptosis. Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS); Muckle-Wells syndrome (MWS); chronic infantile neurological cutaneous and articular (CINCA) syndrome; and neonatal-onset multisystem inflammatory disease (NOMID). Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Alternative 5' UTR structures are suggested by available data; however; insufficient evidence is available to determine if all of the represented 5' UTR splice patterns are biologically valid. [provided by RefSeq; Oct 2008]
- Host:
- HEK293
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
