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Recombinant Human AREG Protein; hFc Tag

Product Sizes
50 µg
£750.00
32-17986-50UG
100 µg
£911.00
32-17986-100UG
About this Product
SKU:
32-17986
Additional Names:
AR; CRDGF; AREGB; SDGF
Extra Details:
Molecular Characterization: AREG(Ser20-Lys187) hFc(Glu99-Ala330)Molecular weight: The protein has a predicted molecular mass of 44.9 kDa after removal of the signal peptide. The apparent molecular mass of AREG-hFc is approximately 53-70 kDa due to glycosylation.Description: Recombinant human AREG protein with C-terminal human Fc tagThe protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes; Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells; and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland; oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype; and is also associated with other pathological disorders; including various types of cancers and inflammatory conditions.
Host:
HEK293
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules