Recombinant Human SEMA4D Protein; His Tag
Product Sizes
50 µg
£750.00
32-17985-50UG
100 µg
£911.00
32-17985-100UG
About this Product
- SKU:
- 32-17985
- Additional Names:
- A8; BB18; GR3; CD100; C9orf164; CD100; SEMAJ
- Extra Details:
- Molecular Characterization: SEMA4D(Met22-Arg734)6Ã-His tagMolecular weight: The protein has a predicted molecular mass of 80 kDa after removal of the signal peptide. The apparent molecular mass of SEMA4D-His is approximately 95-130 kDa due to glycosylation.Description: Recombinant human SEMA4D protein with C-terminal6Ã-His tagCell surface receptor for PLXNB1 and PLXNB2 that plays an important role in cell-cell signaling (PubMed: 20877282). Regulates GABAergic synapse development (By similarity). Promotes the development of inhibitory synapses in a PLXNB1-dependent manner (By similarity). Modulates the complexity and arborization of developing neurites in hippocampal neurons by activating PLXNB1 and interaction with PLXNB1 mediates activation of RHOA (PubMed: 19788569). Promotes the migration of cerebellar granule cells (PubMed: 16055703). Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro) (PubMed: 8876214). Induces endothelial cell migration through the activation of PTK2B/PYK2; SRC; and the phosphatidylinositol 3-kinase-AKT pathway (PubMed: 16055703).[UniProtKB/Swiss-Prot Function]
- Host:
- HEK293
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
