Recombinant Human NPR1 Protein; hFc Tag
Product Sizes
50 µg
£823.00
32-17980-50UG
100 µg
£1019.00
32-17980-100UG
About this Product
- SKU:
- 32-17980
- Additional Names:
- ANP-A; ANPR-A; ANPRA; NPR-A; GC-A
- Extra Details:
- Molecular Characterization: NPR1(Gly33-Glu473) hFc(Glu99-Ala330)Molecular weight: The protein has a predicted molecular mass of 75.0 kDa after removal of the signal peptide. The apparent molecular mass of NPR1-hFc is approximately 95-130 kDa due to glycosylation.Description: Recombinant human NPR1 protein with C-terminal human Fc tagGuanylyl cyclases; catalyzing the production of cGMP from GTP; are classified as soluble and membrane forms (Garbers and Lowe; 1994 [PubMed 7982997]). The membrane guanylyl cyclases; often termed guanylyl cyclases A through F; form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain; a single membrane-spanning domain; and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides; they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2; MIM 108961). Also see NPR3 (MIM 108962); which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP (MIM 108780) and BNP (MIM 600295); respectively).[supplied by OMIM; May 2009]
- Host:
- HEK293
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
