Recombinant Mouse CD40 Ligand Protein; hFc Tag
Product Sizes
50 µg
£750.00
32-17958-50UG
100 µg
£911.00
32-17958-100UG
About this Product
- SKU:
- 32-17958
- Additional Names:
- CD40-L; TRAP; CD154; Cd40lg
- Extra Details:
- Molecular Characterization: hFc(Glu99-Ala330) Mouse CD40 Ligand(Gly115-Leu260)Molecular weight: The protein has a predicted molecular mass of 42.1 kDa after removal of the signal peptide. The apparent molecular mass of hFc-CD40L is approximately 40-55 kDa due to glycosylation.Description: Recombinant mouse CD40L protein with N-terminal human Fc tagCytokine that binds to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation. Induces the activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4. Involved in immunoglobulin class switching (PubMed: 1374165).[UniProtKB/Swiss-Prot Function]
- Host:
- HEK293
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
