Recombinant Human PLAUR Protein; His Tag
Product Sizes
50 µg
£805.00
32-17943-50UG
100 µg
£994.00
32-17943-100UG
About this Product
- SKU:
- 32-17943
- Additional Names:
- U-PAR; uPAR; CD87
- Extra Details:
- Molecular Characterization: PLAUR(Leu23-Arg303)6Ã-His tagMolecular weight: The protein has a predicted molecular mass of 32.1 kDa after removal of the signal peptide. The apparent molecular mass of PLAUR-His is approximately 35-55 kDa due to glycosylation.Description: Recombinant human PLAUR protein with C-terminal6Ã-His tagThis gene encodes the receptor for urokinase plasminogen activator and; given its role in localizing and promoting plasmin formation; likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However; a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.
- Host:
- HEK293
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
