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Recombinant Human RSPO1(21-263) Protein; His Tag

Product Sizes
50 µg
£805.00
32-17932-50UG
100 µg
£994.00
32-17932-100UG
About this Product
SKU:
32-17932
Additional Names:
R-spondin-1; hRspo1
Extra Details:
Molecular Characterization: RSPO1(21-263)(Ser21-Ala263)6Ã-His tagMolecular weight: The protein has a predicted molecular mass of 27.6 kDa after removal of the signal peptide. The apparent molecular mass of RSPO1(21-263)-His is approximately 35-55 kDa due to glycosylation.Description: Recombinant human RSPO1(21-263) protein with C-terminal6Ã-His tagThis gene encodes a secreted activator protein with two cysteine-rich; furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice; the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing; providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants.
Host:
HEK293
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules