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Recombinant Mouse TIM3 Protein; hFc Tag

Product Sizes
50 µg
£750.00
32-17915-50UG
100 µg
£911.00
32-17915-100UG
About this Product
SKU:
32-17915
Additional Names:
HAVCR2; TIMD3; FLJ14428; KIM3
Extra Details:
Molecular Characterization: Mouse TIM3(Arg20-Thr192) hFc(Glu99-Ala330)Molecular weight: The protein has a predicted molecular mass of 45.4 kDa after removal of the signal peptide. The apparent molecular mass of mTIM3-hFc is approximately 55-70 kDa due to glycosylation.Description: Recombinant mouse TIM3 protein with C-terminal human Fc tagThe protein encoded by this gene belongs to the immunoglobulin superfamily; and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions; whereas; Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation; and inhibits Th1-mediated auto- and alloimmune responses; and promotes immunological tolerance.
Host:
HEK293
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules