Recombinant Mouse B7-2 Protein; hFc Tag
Product Sizes
50 µg
£750.00
32-17913-50UG
100 µg
£911.00
32-17913-100UG
About this Product
- SKU:
- 32-17913
- Additional Names:
- CD86; ETC-1
- Extra Details:
- Molecular Characterization: Mouse B7-2(Val24-Glu245) hFc(Glu99-Ala330)Molecular weight: The protein has a predicted molecular mass of 51.4 kDa after removal of the signal peptide. The apparent molecular mass of mB7-2-hFc is approximately 55-70 kDa due to glycosylation.Description: Recombinant mouse B7-2 protein with C-terminal human Fc tagThis gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells; and it is the ligand for two proteins at the cell surface of T cells; CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
- Host:
- HEK293
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
