Recombinant Human ITGAX & ITGB2 Heterodimer Protein; His Tag & hFc Tag
Product Sizes
50 µg
£823.00
32-17895-50UG
100 µg
£1018.00
32-17895-100UG
About this Product
- SKU:
- 32-17895
- Additional Names:
- Integrin alpha-X&Integrin beta-2
- Extra Details:
- Molecular Characterization: ITGAX(Phe20-Pro1107)6Ã-His tag and ITGB2(Gln23-Asn700) hFc(Glu99-Ala330)Molecular weight: The protein has a predicted molecular mass of 120.6 and 101.0 kDa after removal of the signal peptide. The apparent molecular mass of ITGAX-His and ITGB2-hFc is approximately 130-180 kDa due to glycosylation.Description: Heterodimer protein contains recombinant human ITGAX protein with C-terminal6Ã-His tag and human ITGB2 protein with C-terminal human Fc tagThis gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells; and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene.
- Host:
- HEK293
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
