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Recombinant Human ADAM15 Protein; hFc Tag

Product Sizes
50 µg
£805.00
32-17889-50UG
100 µg
£994.00
32-17889-100UG
About this Product
SKU:
32-17889
Additional Names:
ADAM 15; MDC-15
Extra Details:
Molecular Characterization: ADAM15(Leu18-Thr696) hFc(Glu99-Ala330)Molecular weight: The protein has a predicted molecular mass of 100.0 kDa after removal of the signal peptide. The apparent molecular mass of ADAM15-hFc is approximately 100-130 kDa due to glycosylation.Description: Recombinant human ADAM15 protein with C-terminal human Fc tagThe protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain; a disintegrin-like domain; as well as a EGF-like domain. Through its disintegrin-like domain; this protein specifically interacts with the integrin beta chain; beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner; suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
Host:
HEK293
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules