Recombinant Human B7-H3 Protein; mFc Tag
Product Sizes
50 µg
£646.00
32-17884-50UG
100 µg
£770.00
32-17884-100UG
About this Product
- SKU:
- 32-17884
- Additional Names:
- B7H3; CD276; 4Ig-B7-H3
- Extra Details:
- Molecular Characterization: B7-H3?Gly27-Thr461?+mFc?Pro99-Lys330? Molecular Weight: The protein has a predicted molecular mass of 72.8 kDa after removal of the signal peptide. The apparent molecular mass of B7-H3-mFc is approximately 70-100 kDa due to glycosylation. Description: Recombinant human B7-H3 protein with C-terminal mouse Fc tag The protein encoded by this gene belongs to the immunoglobulin superfamily; and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors; the protein is preferentially expressed only in tumor tissues. Additionally; it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA; and there is an inverse correlation between the expression of this protein and miR29 levels; suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Host:
- HEK293
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
