Recombinant Human MUC18 Protein; His Tag
Product Sizes
50 µg
£646.00
32-17863-50UG
100 µg
£770.00
32-17863-100UG
About this Product
- SKU:
- 32-17863
- Additional Names:
- Cell surface glycoprotein MUC18?Cell surface glycoprotein P1H12?Melanoma cell adhesion molecule?Melanoma-associated antigen A32?Melanoma-associated antigen MUC18?S-endo 1 endothelial-associated antigen?CD146
- Extra Details:
- Molecular Characterization: MUC18(Val24-Gly559)6Ã-His tagMolecular weight: The protein has a predicted molecular mass of 60.6 kDa after removal of the signal peptide. The apparent molecular mass of MUC18-His is approximately 70-100 kDa due to glycosylation.Description: Recombinant human MUC18 protein with C-terminal6Ã-His tagPlays a role in cell adhesion; and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system; thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1; and a transient increase in the intracellular calcium concentration.[UniProtKB/Swiss-Prot Function]
- Host:
- HEK293
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
