Recombinant Human PRNP(90-230) Protein; hFc Tag
Product Sizes
50 µg
£646.00
32-17859-50UG
100 µg
£770.00
32-17859-100UG
About this Product
- SKU:
- 32-17859
- Additional Names:
- PrP; ASCR; PrP27-30; PrP33-35C; CD230
- Extra Details:
- Molecular Characterization: PRNP(Gly90-Ser230) hFc(Glu99-Ala330)Molecular weight: The protein has a predicted molecular mass of 42.2 kDa after removal of the signal peptide. The apparent molecular mass of PRNP(90-230)-hFc is approximately 55-70 kDa due to glycosylation.Description: Recombinant human PRNP(90-230) protein with C-terminal human Fc tagThe protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20; approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease; fatal familial insomnia; Gerstmann-Straussler disease; Huntington disease-like 1; and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller; structurally unrelated protein; AltPrp. Alternative splicing results in multiple transcript variants.
- Host:
- HEK293
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
