Recombinant Human MMP13 Protein; His Tag
Product Sizes
50 µg
£805.00
32-17817-50UG
100 µg
£994.00
32-17817-100UG
About this Product
- SKU:
- 32-17817
- Additional Names:
- MMP-13; Collagenase 3; Matrix metalloproteinase-13
- Extra Details:
- Molecular Characterization: MMP13(Leu20-Cys471)6Ã-His tagMolecular weight: The protein has a predicted molecular mass of 52.5 kDa after removal of the signal peptide. The apparent molecular mass of MMP13-His is approximately 55-70 kDa due to glycosylation.Description: Recombinant human MMP13 Protein with C-terminal6Ã-His tagThis gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes; such as embryonic development; reproduction; and tissue remodeling; as well as in disease processes; such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. Mutations in this gene are associated with metaphyseal anadysplasia. This gene is part of a cluster of MMP genes on chromosome 11.
- Host:
- HEK293
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Assay Kits:MMP
- Manufacturer's Data Sheet:download_pdf.php
