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Recombinant Mouse HBEGF (24-160) Protein; His Tag

Product Sizes
50 µg
£646.00
32-17704-50UG
100 µg
£770.00
32-17704-100UG
About this Product
SKU:
32-17704
Additional Names:
AW047313; Dtr; Dts; Hegfl
Extra Details:
Molecular Characterization: Mouse HBEGF(24-160)(Gln24-Thr160)6Ã-His tagMolecular weight: The protein has a predicted molecular mass of 16.0 kDa after removal of the signal peptide.The apparent molecular mass of mHBEGF(24-160)-His is approximately 25-35 kDa due to glycosylation.Description: Recombinant mouse HBEGF(24-160) protein with C-terminal6Ã-His tagGrowth factor that mediates its effects via EGFR; ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts; but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.[UniProtKB/Swiss-Prot Function]
Host:
HEK293
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules