Recombinant Mouse HBEGF (24-160) Protein; hFc Tag
Product Sizes
50 µg
£646.00
32-17698-50UG
100 µg
£770.00
32-17698-100UG
About this Product
- SKU:
- 32-17698
- Additional Names:
- AW047313; Dtr; Dts; Hegfl
- Extra Details:
- Molecular Characterization: Mouse HBEGF(24-160)(Gln24-Thr160) hFc(Glu99-Ala330)Molecular weight: The protein has a predicted molecular mass of 41.3 kDa after removal of the signal peptide.The apparent molecular mass of mHBEGF(24-160)-hFc is approximately 40-55 kDa due to glycosylation.Description: Recombinant mouse HBEGF(24-160) protein with C-terminal human Fc tagGrowth factor that mediates its effects via EGFR; ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts; but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.[UniProtKB/Swiss-Prot Function]
- Host:
- HEK293
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
