Recombinant Human GPC3 Protein; hFc Tag
Product Sizes
50 µg
£805.00
32-17696-50UG
100 µg
£994.00
32-17696-100UG
About this Product
- SKU:
- 32-17696
- Additional Names:
- DGSX; GTR2-2; MXR7; OCI-5; SDYS; SGB; SGBS; SGBS1
- Extra Details:
- Molecular Characterization: hFc(Glu99-Ala330) GPC3(Asp511-Ser560)Molecular weight: The protein has a predicted molecular mass of 43.3 kDa after removal of the signal peptide.Description: Recombinant Human GPC3 Protein with N-terminal Human Fc tagCell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26; and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome; also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. Referencesï¼Å¡ Fu Ying;Urban Daniel J;Nani Roger R et al. Glypican-3-Specific Antibody Drug Conjugates Targeting Hepatocellular Carcinoma.[J] .Hepatology; 2019; 70: 563-576. Zhang Yi-Fan;Ho Mitchell;Humanization of high-affinity antibodies targeting glypican-3 in hepatocellular carcinoma.[J] .Sci Rep; 2016; 6: 33878.
- Host:
- HEK293
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
