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Recombinant Human GFRAL Protein; His Tag

Product Sizes
50 µg
£688.00
32-17680-50UG
100 µg
£832.00
32-17680-100UG
About this Product
SKU:
32-17680
Additional Names:
bA360D14.1; C6orf144; GRAL; UNQ9356
Extra Details:
Molecular Characterization: GFRAL(Ser19-Glu351)6Ã-His tagMolecular weight: The protein has a predicted molecular mass of 38.6 kDa after removal of the signal peptide. The apparent molecular mass of GFRAL-His is approximately 35-55 kDa due to glycosylation.Description: Recombinant human GFRAL protein with C-terminal6Ã-His tagBrainstem-restricted receptor for GDF15 which regulates food intake; energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed: 28953886; PubMed: 28846097; PubMed: 28846098; PubMed: 28846099). Upon interaction with its ligand; GDF15; interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways.[UniProtKB/Swiss-Prot Function]
Host:
HEK293
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg