Recombinant Human UPA Protein; His Tag
Product Sizes
50 µg
£649.00
32-17662-50UG
100 µg
£771.00
32-17662-100UG
About this Product
- SKU:
- 32-17662
- Additional Names:
- ATF; BDPLT5; QPD; u-PA; UPA; URK
- Extra Details:
- Molecular Characterization: UPA?Ser21-Leu431?+6×His tag Molecular Weight: The protein has a predicted molecular mass of 47.2 kDa after removal of the signal peptide. The apparent molecular mass of UPA-His is approximately 55-70 kDa due to glycosylation. Description: Recombinant human UPA protein with C-terminal6Ã-His tag This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants; at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq; Jan 2016]
- Host:
- HEK293
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
