Recombinant Human IL21R Protein; His Tag
Product Sizes
50 µg
£688.00
32-17647-50UG
100 µg
£832.00
32-17647-100UG
About this Product
- SKU:
- 32-17647
- Additional Names:
- CD360; IMD56; NILR
- Extra Details:
- Molecular Characterization: IL21R(Cys20-Glu232)6Ã-His tagMolecular weight: The protein has a predicted molecular mass of 25.4 kDa after removal of the signal peptide.The apparent molecular mass of IL21R-His is approximately 35-55 kDa due to glycosylation.Description: Recombinant Human IL21R with C-terminal6Ã-His tagThe protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors; and has been shown to form a heterodimeric receptor complex with the common gamma-chain; a receptor subunit also shared by the receptors for interleukin 2; 4; 7; 9; and 15. This receptor transduces the growth promoting signal of IL21; and is important for the proliferation and differentiation of T cells; B cells; and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules; including JAK1; JAK3; STAT1; and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.
- Host:
- HEK293
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
