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Recombinant Human SLC7A11 Protein; hFc Tag

Product Sizes
50 µg
£649.00
32-17645-50UG
100 µg
£771.00
32-17645-100UG
About this Product
SKU:
32-17645
Additional Names:
CCBR1; xCT
Extra Details:
Molecular Characterization: SLC7A11(Lys67-Gly74) (Leu151-Cys158) (Lys215-Thr233) hFc(Glu99-Ala330) Molecular weight: The protein has a predicted molecular mass of 33.4 kDa after removal of the signal peptide.The apparent molecular mass of SLC7A11-hFc is approximately 35-55 kDa due to glycosylation. Description: Recombinant Human SLC7A11 Protein with C-terminal human Fc tag This gene encodes a member of a heteromeric; sodium-independent; anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system; designated Xc(-); the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also; increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels; resulting in neuronal cell death.
Host:
HEK293
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules