Recombinant Human GM-CSF Protein; hFc Tag
Product Sizes
50 µg
£805.00
32-17644-50UG
100 µg
£994.00
32-17644-100UG
About this Product
- SKU:
- 32-17644
- Additional Names:
- CSF; GMCSF
- Extra Details:
- Molecular Characterization: GM-CSF(Ala18-Glu144) hFc(Glu99-Ala330)Molecular weight: The protein has a predicted molecular mass of 40.6 kDa after removal of the signal peptide.The apparent molecular mass of GM-CSF-hFc is approximately 35-70 kDa due to glycosylation.Description: Recombinant Human GM-CSF Protein with C-terminal human Fc tagThe protein encoded by this gene is a cytokine that controls the production; differentiation; and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31; which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4; 5; and 13. This gene plays a role in promoting tissue inflammation. Elevated levels of cytokines; including the one produced by this gene; have been detected in SARS-CoV-2 infected patients that develop acute respiratory distress syndrome. Mice deficient in this gene or its receptor develop pulmonary alveolar proteinosis.
- Host:
- HEK293
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
