Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout

Recombinant Human IL18 Protein; mFc Tag

Product Sizes
50 µg
£805.00
32-17632-50UG
100 µg
£994.00
32-17632-100UG
About this Product
SKU:
32-17632
Additional Names:
IGIF; IL-1g; IL-18; IL1F4
Extra Details:
Molecular Characterization: IL18(Thr37-Asp197) mFc(Pro99-Lys330)Molecular weight: The protein has a predicted molecular mass of 44.3 kDa after removal of the signal peptide.The apparent molecular mass of IL18-mFc is approximately 35-55 kDa due to glycosylation.Description: Recombinant Human IL18 with C-terminal mouse Fc tagThe protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1; and is capable of stimulating interferon gamma production; and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs; and in potentially fatal conditions characterized by a cytokine storm. In humans; IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Host:
HEK293
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules