Recombinant Human PSMA Protein; His Tag
Product Sizes
50 µg
£862.00
32-17618-50UG
100 µg
£1075.00
32-17618-100UG
About this Product
- SKU:
- 32-17618
- Additional Names:
- FGCP; FOLH; GCP2; GCPII; mGCP; NAALAD1; NAALAdase; PSM; PSMA
- Extra Details:
- Molecular Characterization:6Ã-His tag PSMA(Lys44-Ala750)Molecular weight: The protein has a predicted molecular mass of 80.3 kDa after removal of the signal peptide.The apparent molecular mass of His-PSMA is approximately 100-130 kDa due to glycosylation.Description: Recombinant human PSMA protein with N-terminal6Ã-His tagThis gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates; including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate; central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates; resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms.
- Host:
- HEK293
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
