Recombinant Human IL5RA Protein; hFc Tag
Product Sizes
50 µg
£688.00
32-17610-50UG
100 µg
£832.00
32-17610-100UG
About this Product
- SKU:
- 32-17610
- Additional Names:
- IL5Ra;CD125;IL-5 R alpha
- Extra Details:
- Molecular Characterization: IL5RA(Asp21-Pro338) hFc(Glu99-Ala330)Molecular weight: The protein has a predicted molecular mass of 62.3 kDa after removal of the signal peptide.The apparent molecular mass of IL5RA-hFc is approximately 70-100 kDa due to glycosylation.Description: Recombinant human L5RA protein with C-terminal human Fc tagThe protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3); colony stimulating factor 2 (CSF2/GM-CSF); and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding; and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin); which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.
- Host:
- HEK293
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
