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Recombinant Human IL6R Protein; hFc Tag

Product Sizes
50 µg
£680.00
32-17609-50UG
100 µg
£815.00
32-17609-100UG
About this Product
SKU:
32-17609
Additional Names:
CD126; gp80; IL-6R-1; IL-6RA; IL6Q; IL6RA; IL6RQ
Extra Details:
Molecular Characterization: IL6R(Leu20-Pro365) hFc(Glu99-Ala330)Molecular weight: The protein has a predicted molecular mass of 64.7 kDa after removal of the signal peptide.The apparent molecular mass of IL6R-hFc is approximately 70-100 kDa due to glycosylation.Description: Recombinant Human IL6R with C-terminal human Fc tagThis gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta); a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases; such as multiple myeloma; autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.
Host:
HEK293
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules