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Recombinant Human LIGHT Protein; hFc Tag

Product Sizes
50 µg
£700.00
32-17607-50UG
100 µg
£851.00
32-17607-100UG
About this Product
SKU:
32-17607
Additional Names:
TNFSF14; CD258? HVEML? LIGHT? LTg
Extra Details:
Molecular Characterization: hFc(Glu99-Ala330) LIGHT(Leu83-Val240)Molecular weight: The protein has a predicted molecular mass of 43.4 kDa after removal of the signal peptide.Description: Recombinant Human LIGHT protein with N-terminal human FcThe protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14; which is a member of the tumor necrosis factor receptor superfamily; and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells; and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported.
Host:
HEK293
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules