Recombinant Mouse BTLA Protein; His Tag
Product Sizes
50 µg
£680.00
32-17605-50UG
100 µg
£815.00
32-17605-100UG
About this Product
- SKU:
- 32-17605
- Additional Names:
- BTLA;CD272
- Extra Details:
- Molecular Characterization: Mouse BTLA(Glu30-Pro176)6Ã-His tagMolecular weight: The protein has a predicted molecular mass of 17.4 kDa after removal of the signal peptide.The apparent molecular mass of Mouse-BTLA-His is approximately 35-55 kDa due to glycosylation.Description: Recombinant mouse BTLA protein with C-terminal6Ã-His tagInhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed: 12796776; PubMed: 14652006). May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14 (PubMed: 19915044). In cis interactions; appears to play an immune regulatory role inhibiting in trans interactions in naive T cells to maintain a resting state. In trans interactions; can predominate during adaptive immune response to provide survival signals to effector T cells (PubMed: 19915044).
- Host:
- HEK293
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
