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Recombinant Human FGFR4 Protein; His Tag

Product Sizes
50 µg
£646.00
32-17586-50UG
100 µg
£770.00
32-17586-100UG
About this Product
SKU:
32-17586
Additional Names:
CD334; JTK2; TKF
Extra Details:
Molecular Characterization: FGFR4(Leu22-Asp369)6Ã-His TagMolecular weight: The protein has a predicted molecular mass of 39.3 kDa after removal of the signal peptide.The apparent molecular mass of FGFR4-His is approximately 35-70 kDa due to glycosylation.Description: Recombinant Human FGFR4 Protein with C-terminal6Ã-His tagThe protein encoded by this gene is a tyrosine kinase and cell surface receptor for fibroblast growth factors. The encoded protein is involved in the regulation of several pathways; including cell proliferation; cell differentiation; cell migration; lipid metabolism; bile acid biosynthesis; vitamin D metabolism; glucose uptake; and phosphate homeostasis. This protein consists of an extracellular region; composed of three immunoglobulin-like domains; a single hydrophobic membrane-spanning segment; and a cytoplasmic tyrosine kinase domain. The extracellular portion interacts with fibroblast growth factors; setting in motion a cascade of downstream signals; ultimately influencing mitogenesis and differentiation.
Host:
HEK293
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules