Human IFNB1 Protein; hFc Tag
Product Sizes
50 µg
£680.00
32-17560-50UG
About this Product
- SKU:
- 32-17560
- Additional Names:
- IFB; IFF; IFN-beta; IFNB
- Extra Details:
- The protein has a predicted molecular mass of 46.2 kDa after removal of the signal peptide. The apparent molecular mass of IFNB1-hFc is approximately 40-55 kDa due to glycosylation. This gene encodes a cytokine that belongs to the interferon family of signaling proteins; which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons; which are important for defense against viral infections. In addition; type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen; type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection.
- Host:
- HEK293
- Purification:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing).Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
