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Human CD74 (73-296) Protein; hFc Tag

Product Sizes
50 µg
£646.00
32-17520-50UG
About this Product
SKU:
32-17520
Additional Names:
DHLAG; HLADG; Ia-GAMMA; II; p33
Extra Details:
The protein has a predicted molecular mass of 51.5 kDa after removal of the signal peptide.The apparent molecular mass of hFc-CD74(73-296) is approximately 55-70 kDa due to glycosylation. The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which; when bound to the encoded protein; initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Host:
HEK293
Purification:
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing).Lyophilized proteins are shipped at ambient temperature.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules