Human EPHB2 Protein; His Tag
Product Sizes
50 µg
£646.00
32-17509-50UG
About this Product
- SKU:
- 32-17509
- Additional Names:
- BDPLT22; CAPB; DRT; EK5; EPHT3; ERK; Hek5; PCBC; Tyro5
- Extra Details:
- The protein has a predicted molecular mass of 58.9 kDa after removal of the signal peptide. The apparent molecular mass of EPHB2-His is approximately 55-70 kDa due to glycosylation. This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain; a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility; division; and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade; resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants.
- Host:
- HEK293
- Purification:
- The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing).Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
