Recombinant human CD43 protein with C-terminal human Fc tag
Product Sizes
50 µg
£680.00
32-17435-50UG
About this Product
- SKU:
- 32-17435
- Additional Names:
- CD43; GALGP; GPL115; LSN
- Extra Details:
- Expression Host : HEK293 The protein has a predicted molecular mass of 51.26 kDa after removal of the signal peptide. This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells; and is found on the surface of thymocytes; T lymphocytes; monocytes; granulocytes; and some B lymphocytes. It contains a mucin-like extracellular domain; a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues; allowing extensive O-glycosylation; and has one potential N-glycosylation site; while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells; proteolytic cleavage of the extracellular domain occurs in some cell types; releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome.
- Purification:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -80[o]C for 12 months (Avoid repeated freezing and thawing)
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
