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Recombinant human CD305 protein with C-terminal human Fc tag

Product Sizes
50 µg
£649.00
32-17421-50UG
About this Product
SKU:
32-17421
Additional Names:
CD305; LAIR-1
Extra Details:
Expression Host : HEK293 The protein has a predicted molecular mass of 41.36 kDa after removal of the signal peptide. The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells; including natural killer cells; T cells; and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster; which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1; and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants.
Purification:
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -80[o]C for 12 months (Avoid repeated freezing and thawing)
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules